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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TYRO3
All Species:
33.94
Human Site:
Y744
Identified Species:
82.96
UniProt:
Q06418
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q06418
NP_006284.2
890
96905
Y744
E
N
A
E
I
Y
N
Y
L
I
G
G
N
R
L
Chimpanzee
Pan troglodytes
XP_515690
1233
133559
Y1046
Q
N
H
E
M
Y
D
Y
L
L
H
G
H
R
L
Rhesus Macaque
Macaca mulatta
XP_001099590
859
93567
Y713
E
N
A
E
I
Y
N
Y
L
I
G
G
N
R
L
Dog
Lupus familis
XP_544633
862
93877
Y716
E
N
A
E
I
Y
N
Y
L
I
G
G
N
R
L
Cat
Felis silvestris
Mouse
Mus musculus
P55144
880
96204
Y734
E
N
A
E
I
Y
N
Y
L
I
G
G
N
R
L
Rat
Rattus norvegicus
P55146
880
95900
Y734
E
N
A
E
I
Y
N
Y
L
I
S
G
N
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520501
363
39917
T223
V
T
M
W
E
I
V
T
R
G
Q
T
P
Y
A
Chicken
Gallus gallus
Q98949
873
96384
Y731
E
N
A
E
I
Y
N
Y
L
I
S
G
N
R
L
Frog
Xenopus laevis
Q8QFP9
880
97916
Y729
E
N
S
E
I
Y
S
Y
L
I
A
G
N
R
L
Zebra Danio
Brachydanio rerio
Q9YI66
874
97580
Y723
E
N
S
E
I
Y
E
Y
L
I
K
G
E
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
32.2
94.9
90.6
N.A.
88.7
88.7
N.A.
33.5
67
58.5
48.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
46.7
95.1
93
N.A.
91.6
91.9
N.A.
36.9
78.7
73.1
63.5
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
53.3
100
100
N.A.
100
93.3
N.A.
0
93.3
80
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
100
93.3
N.A.
0
93.3
93.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
60
0
0
0
0
0
0
0
10
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
80
0
0
90
10
0
10
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
40
90
0
0
0
% G
% His:
0
0
10
0
0
0
0
0
0
0
10
0
10
0
0
% H
% Ile:
0
0
0
0
80
10
0
0
0
80
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
90
10
0
0
0
0
90
% L
% Met:
0
0
10
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
90
0
0
0
0
60
0
0
0
0
0
70
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
90
0
% R
% Ser:
0
0
20
0
0
0
10
0
0
0
20
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% T
% Val:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
90
0
90
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _